Nootropic Peptides

For laboratory and research use only — not for human consumption. All content is educational.

Peptide library

All 46 research peptides

Fifteen peptides covering cognitive enhancement, neuroprotection, anxiolytic effects, sleep modulation, and neurogenesis. All entries are for laboratory research reference only.

Cognitive Enhancement

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Cognitive EnhancementIntranasal: minutes (peptide)

Semax

A synthetic heptapeptide analogue of ACTH(4-10) developed in Russia for cognitive enhancement, neuroprotection, and stroke recovery research.

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Cognitive EnhancementOral bioavailability

Noopept (Peptide Note)

A small proline-containing dipeptide derivative — technically a peptidomimetic — developed in Russia as an orally active cognitive enhancer with structural lineage to piracetam.

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Cognitive EnhancementSubstantially extended relative to parent Semax

N-Acetyl Semax Amidate

A chemically protected analogue of Semax with N-terminal acetylation and C-terminal amidation, conferring substantially extended half-life and improved potency in research.

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Cognitive EnhancementShort plasma half-life

Cycloprolylglycine

An endogenous cyclic dipeptide that is also the primary active metabolite of Noopept, with intrinsic anxiolytic and cognitive effects independent of its parent compound — a research peptide in its own right.

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Cognitive EnhancementApproximately 30-40 minutes plasma

Tesamorelin

A licensed GHRH(1-44) analogue with a positive cognitive-effect trial in HIV-associated neurocognitive disorder — the strongest cognitive-endpoint evidence in the GH-axis peptide family.

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Cognitive EnhancementApproximately 75 minutes (intranasal)

DDAVP (Desmopressin)

A licensed synthetic vasopressin analogue with documented memory-modulation effects — one of the classical vasopressin-family cognitive research peptides with the deepest historical literature.

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Cognitive EnhancementShort plasma half-life

DGAVP

A classical De Wied-laboratory vasopressin analogue engineered to preserve memory-relevant central effects while eliminating the pressor effect of parent vasopressin — the reference vasopressin-family cognitive research peptide of the 1970s-80s.

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Cognitive EnhancementShort plasma half-life

Org 2766

A classical Dutch/Organon ACTH(4-9) analogue closely related to Semax — the direct pharmacological cousin of the Russian cognitive-peptide programme's flagship compound, with independent memory and neuroprotective research history.

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Cognitive EnhancementShort plasma half-life (minutes)

ACTH(4-10)

The parent 4-10 fragment of adrenocorticotropic hormone from which Semax derives — the classical ACTH-fragment cognitive-research peptide with foundational historical significance in the vasopressin/ACTH memory-peptide programme.

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Cognitive EnhancementShort plasma half-life

MIF-1

A tripeptide originally identified as an inhibitor of melanocyte-stimulating hormone release, with a distinctive research history spanning memory modulation, dopamine-receptor allosteric effects, and Parkinson's-disease-adjacent research applications.

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Cognitive EnhancementVery short plasma half-life (minutes)

TRH (Thyrotropin-releasing hormone)

The endogenous hypothalamic tripeptide that stimulates thyroid-stimulating hormone release, with distinctive research history in cognitive effects, arousal, mood modulation, and neuroprotective applications separated from the primary thyroid-axis pharmacology.

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Cognitive EnhancementVery short plasma half-life (approximately 10-20 minutes)

Vasopressin

The endogenous nonapeptide antidiuretic hormone with distinctive central memory-modulation effects — the parent compound of the classical vasopressin-family cognitive research programme and the direct hormone from which DDAVP and DGAVP were engineered.

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Neuroprotection

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NeuroprotectionShort plasma half-life

Pinealon

A short tripeptide bioregulator studied in Russian gerontology research for neuroprotective and anti-ageing effects on the central nervous system.

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NeuroprotectionMultiple components with varied pharmacokinetics

Cerebrolysin

A complex mixture of low-molecular-weight peptides and free amino acids derived from porcine brain tissue, studied extensively in cognitive decline and post-stroke recovery research.

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NeuroprotectionShort plasma half-life

Epitalon

A short synthetic tetrapeptide developed in the Khavinson bioregulator programme, studied for telomere maintenance, pineal regulation, and indirect cognitive effects via circadian and stress-resilience pathways.

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NeuroprotectionMulti-component preparation with varied pharmacokinetics

Cortexin

A standardised low-molecular-weight peptide preparation derived from bovine cerebral cortex, used in Russian clinical practice for cognitive impairment, post-stroke recovery, and traumatic brain injury research — the closest single sister to Cerebrolysin.

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NeuroprotectionShort plasma half-life

BPC-157

A synthetic 15-amino-acid peptide derived from a fragment of human gastric juice protein, studied for tissue-repair, gut-brain-axis, and emerging neuroprotective and cognitive-relevant effects.

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NeuroprotectionApproximately 7 days plasma (extended-acting formulation)

Semaglutide

A long-acting GLP-1 receptor agonist licensed for type-2 diabetes and obesity, with an active Phase III cognitive-endpoint trial in Alzheimer's disease (EVOKE) — the highest-profile emerging cognitive-relevance peptide of the 2020s.

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NeuroprotectionShort plasma half-life

SS-31 (Elamipretide)

A mitochondrially-targeted tetrapeptide that binds cardiolipin on the inner mitochondrial membrane, studied for mitochondrial-dysfunction diseases and emerging cognitive-ageing research applications.

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NeuroprotectionShort plasma half-life

Cortagen

A synthetic tetrapeptide from the Khavinson bioregulator programme (Ala-Glu-Asp-Pro), positioned as a brain-cortex-targeted bioregulator complementing Pinealon and Cortexin.

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NeuroprotectionShort plasma half-life

TB-500 (Thymosin Beta-4 fragment)

A synthetic fragment of the endogenous 43-amino-acid thymosin β4 protein, studied for tissue-repair, angiogenesis, and emerging CNS regeneration and neuroprotection applications.

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NeuroprotectionShort plasma half-life

Humanin

A 21-24-amino-acid mitochondrial-derived peptide with cytoprotective and neuroprotective activity — the flagship member of the mitochondrial-derived peptide family, with emerging evidence in Alzheimer's disease and cognitive-ageing research.

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NeuroprotectionShort plasma half-life

Vesugen

A Khavinson vascular short peptide (Lys-Glu-Asp) targeting vascular-endothelial gene expression, with cerebrovascular research relevance in cognitive-ageing and stroke-recovery contexts.

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NeuroprotectionComplex preparation with multiple components and varied pharmacokinetics

Endoluten

A Khavinson pineal peptide preparation covering the pineal-gland-directed bioregulator angle alongside Epitalon — used in Russian gerontology practice for circadian and gerontoprotective effects.

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NeuroprotectionSubstantially extended relative to parent Epitalon

N-Acetyl Epitalon Amidate

A chemically protected analogue of Epitalon with N-terminal acetylation and C-terminal amidation — same pineal-directed pharmacology as parent Epitalon with extended half-life, mirroring the NA-Semax and NA-Selank pattern.

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NeuroprotectionApproximately 13 hours plasma

Liraglutide

The predecessor long-acting GLP-1 receptor agonist to semaglutide, with the completed ELAD Phase II trial in Alzheimer's disease — the reference cognitive-endpoint trial for the GLP-1 class before EVOKE.

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NeuroprotectionMulti-component preparation with varied pharmacokinetics

Cellex

A Russian/Belarusian porcine-brain-derived sialic-acid peptide preparation used clinically for neurological indications, similar in architecture to Cerebrolysin but with a distinct compositional and clinical positioning.

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NeuroprotectionShort plasma half-life

KPV

The α-MSH 11-13 tripeptide fragment (Lys-Pro-Val) with anti-inflammatory activity mediated through melanocortin-receptor-adjacent mechanisms — studied for gut, skin, and emerging neuroinflammation research applications.

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NeuroprotectionShort plasma half-life

Thymulin

A zinc-bound nonapeptide thymic hormone with distinctive research applications spanning immune-cognitive research, sickness-behaviour research, and neuroinflammation-mediated cognitive-decline contexts.

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NeuroprotectionShort plasma half-life owing to serum carnosinase

Carnosine

An endogenous dipeptide (β-alanyl-L-histidine) with distinctive antioxidant, anti-glycation, and metal-chelating properties supporting cellular-protection research applications spanning neuroprotection, cognitive-ageing, and metabolic-cognitive contexts.

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Sleep & Recovery

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Sleep & RecoveryShort plasma half-life (under 10 min)

DSIP

A nonapeptide originally isolated from the cerebral venous blood of sleeping rabbits, studied for sleep modulation, stress resilience, and indirect cognitive effects.

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Sleep & RecoveryWith DAC: ~8 days plasma

CJC-1295

A modified GHRH(1-29) analogue commonly stacked with GH-releasing peptides for GH-axis research, with an indirect cognitive-relevance angle via sleep-architecture support and IGF-1 signalling.

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Sleep & RecoveryApproximately 2 hours plasma

Ipamorelin

A selective ghrelin-receptor agonist growth-hormone-releasing peptide, most commonly stacked with CJC-1295 for physiological GH-pulse research — the reference selective GHRP in modern research practice.

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Sleep & RecoveryApproximately 12 minutes plasma

Sermorelin

The 1-29 amino acid fragment of endogenous growth hormone-releasing hormone (GHRH), historically licensed for paediatric growth hormone deficiency diagnostics and long the reference GHRH research analogue prior to CJC-1295's dominance.

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Sleep & RecoveryApproximately 55 minutes plasma

Hexarelin

A synthetic hexapeptide growth-hormone-releasing peptide with the most potent GH-releasing activity in the class, and distinctive cardioprotective effects mediated by a non-GH-mediated mechanism.

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Sleep & RecoveryApproximately 15-20 minutes plasma

GHRP-2

The reference growth-hormone-releasing peptide developed as a diagnostic and research tool for GH-axis characterisation, with well-established GH-releasing pharmacology and licensed diagnostic use in some jurisdictions.

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Neurogenesis

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NeurogenesisOral bioavailability with extended pharmacodynamic effects

Dihexa

An orally active hexapeptide derivative of angiotensin IV, characterised in academic research as among the most potent known pro-cognitive compounds in animal models.

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NeurogenesisPharmacodynamic effects extend beyond plasma exposure

FGL Peptide

A 15-amino-acid peptide mimetic of the FGL loop of the neural cell adhesion molecule (NCAM), studied for neurogenic, synaptogenic, and memory-enhancing effects in cellular and animal research.

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NeurogenesisPharmacodynamic effects on neurogenesis extend across weeks despite shorter plasma exposure

P21

A small peptide derived from a neurotrophic-cytokine framework, characterised in academic research for hippocampal neurogenesis induction and anti-neuroinflammatory effects in models of cognitive ageing and Alzheimer-type pathology.

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NeurogenesisShort plasma half-life

GHK-Cu (cognitive angle)

A naturally occurring tripeptide-copper complex best known for skin and tissue-repair effects, but with a distinct cognitive-research literature covering gene-expression modulation, antioxidant defence, and indirect neurotrophic effects.

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NeurogenesisShort plasma half-life

Davunetide

An 8-amino-acid ADNP-derived peptide (NAPVSIPQ) evaluated in multiple neurodegenerative disease trials — the flagship clinical-trial peptide in the synaptogenic / neuroprotective family.

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NeurogenesisShort plasma half-life

ARA-290 (Cibinetide)

An 11-amino-acid non-erythropoietic EPO analogue, studied for tissue-protective and neuroprotective effects mediated by the innate repair receptor (IRR) — a distinctive mechanism separated from EPO's erythropoietic activity.

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NeurogenesisApproximately 20-30 hours plasma (vs ~10 minutes for native IGF-1)

IGF-1 LR3

A synthetic long-acting analogue of insulin-like growth factor 1 with reduced IGF-binding-protein affinity, providing sustained systemic IGF-1 signalling with direct hippocampal-neurogenesis implications.

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