Nootropic Peptides

Educational reference only — not medical advice. Compounds with no UK marketing authorisation and no other lawful UK use (for example as a food supplement or cosmetic ingredient) are not for human consumption; this describes UK status only.

Mechanism tag

Neuroprotective peptides

Peptides studied in ischaemic, oxidative, and excitotoxic injury models for their capacity to protect neurons from acute damage.

Neuroprotection

Pinealon

A short tripeptide bioregulator studied in Russian gerontology research for neuroprotective and anti-ageing effects on the central nervous system.

Read profile
Neuroprotection

Cerebrolysin

A complex mixture of low-molecular-weight peptides and free amino acids derived from porcine brain tissue, studied extensively in cognitive decline and post-stroke recovery research.

Read profile
Sleep & Recovery

DSIP

A nonapeptide originally isolated from the cerebral venous blood of sleeping rabbits, studied for sleep modulation, stress resilience, and indirect cognitive effects.

Read profile
Neurogenesis

FGL Peptide

A 15-amino-acid peptide mimetic of the FGL loop of the neural cell adhesion molecule (NCAM), studied for neurogenic, synaptogenic, and memory-enhancing effects in cellular and animal research.

Read profile
Neuroprotection

Epitalon

A short synthetic tetrapeptide developed in the Khavinson bioregulator programme, studied for telomere maintenance, pineal regulation, and indirect cognitive effects via circadian and stress-resilience pathways.

Read profile
Neuroprotection

Cortexin

A standardised low-molecular-weight peptide preparation derived from bovine cerebral cortex, used in Russian clinical practice for cognitive impairment, post-stroke recovery, and traumatic brain injury research — the closest single sister to Cerebrolysin.

Read profile
Neurogenesis

P21

A small peptide derived from a neurotrophic-cytokine framework, characterised in academic research for hippocampal neurogenesis induction and anti-neuroinflammatory effects in models of cognitive ageing and Alzheimer-type pathology.

Read profile
Neurogenesis

GHK-Cu (cognitive angle)

A naturally occurring tripeptide-copper complex best known for skin and tissue-repair effects, but with a distinct cognitive-research literature covering gene-expression modulation, antioxidant defence, and indirect neurotrophic effects.

Read profile
Neuroprotection

BPC-157

A synthetic 15-amino-acid peptide derived from a fragment of human gastric juice protein, studied for tissue-repair, gut-brain-axis, and emerging neuroprotective and cognitive-relevant effects.

Read profile
Cognitive Enhancement

Tesamorelin

A licensed GHRH(1-44) analogue with a positive cognitive-effect trial in HIV-associated neurocognitive disorder — the strongest cognitive-endpoint evidence in the GH-axis peptide family.

Read profile
Neurogenesis

Davunetide

An 8-amino-acid ADNP-derived peptide (NAPVSIPQ) evaluated in multiple neurodegenerative disease trials — the flagship clinical-trial peptide in the synaptogenic / neuroprotective family.

Read profile
Neuroprotection

Semaglutide

A long-acting GLP-1 receptor agonist licensed for type-2 diabetes and obesity, with Phase III Alzheimer's disease trials (EVOKE and EVOKE Plus) that did not show slowed clinical progression (Lancet, 2026).

Read profile
Neuroprotection

SS-31 (Elamipretide)

A mitochondrially-targeted tetrapeptide that binds cardiolipin on the inner mitochondrial membrane, studied for mitochondrial-dysfunction diseases and emerging cognitive-ageing research applications.

Read profile
Neuroprotection

Cortagen

A synthetic tetrapeptide from the Khavinson bioregulator programme (Ala-Glu-Asp-Pro), positioned as a brain-cortex-targeted bioregulator complementing Pinealon and Cortexin.

Read profile
Neuroprotection

TB-500 (Thymosin Beta-4 fragment)

A synthetic fragment of the endogenous 43-amino-acid thymosin β4 protein, studied for tissue-repair, angiogenesis, and emerging CNS regeneration and neuroprotection applications.

Read profile
Neurogenesis

ARA-290 (Cibinetide)

An 11-amino-acid non-erythropoietic EPO analogue, studied for tissue-protective and neuroprotective effects mediated by the innate repair receptor (IRR) — a distinctive mechanism separated from EPO's erythropoietic activity.

Read profile
Neuroprotection

Humanin

A 21-24-amino-acid mitochondrial-derived peptide with cytoprotective and neuroprotective activity — the flagship member of the mitochondrial-derived peptide family, with emerging evidence in Alzheimer's disease and cognitive-ageing research.

Read profile
Neuroprotection

Vesugen

A Khavinson vascular short peptide (Lys-Glu-Asp) targeting vascular-endothelial gene expression, with cerebrovascular research relevance in cognitive-ageing and stroke-recovery contexts.

Read profile
Neuroprotection

Endoluten

A Khavinson pineal peptide preparation covering the pineal-gland-directed bioregulator angle alongside Epitalon — used in Russian gerontology practice for circadian and gerontoprotective effects.

Read profile
Neuroprotection

N-Acetyl Epitalon Amidate

A chemically protected analogue of Epitalon with N-terminal acetylation and C-terminal amidation — same pineal-directed pharmacology as parent Epitalon with extended half-life, mirroring the NA-Semax and NA-Selank pattern.

Read profile
Neuroprotection

Liraglutide

The predecessor long-acting GLP-1 receptor agonist to semaglutide, with the completed ELAD Phase II trial in Alzheimer's disease — the reference cognitive-endpoint trial for the GLP-1 class before EVOKE.

Read profile
Neuroprotection

Cellex

A Russian/Belarusian porcine-brain-derived sialic-acid peptide preparation used clinically for neurological indications, similar in architecture to Cerebrolysin but with a distinct compositional and clinical positioning.

Read profile
Neuroprotection

KPV

The α-MSH 11-13 tripeptide fragment (Lys-Pro-Val) with anti-inflammatory activity mediated through melanocortin-receptor-adjacent mechanisms — studied for gut, skin, and emerging neuroinflammation research applications.

Read profile
Neuroprotection

Thymulin

A zinc-bound nonapeptide thymic hormone with distinctive research applications spanning immune-cognitive research, sickness-behaviour research, and neuroinflammation-mediated cognitive-decline contexts.

Read profile
Neuroprotection

Carnosine

An endogenous dipeptide (β-alanyl-L-histidine) with distinctive antioxidant, anti-glycation, and metal-chelating properties supporting cellular-protection research applications spanning neuroprotection, cognitive-ageing, and metabolic-cognitive contexts.

Read profile