Mechanism tag
Oral-active peptides
Peptides or peptidomimetics that survive gastrointestinal proteolysis and reach the CNS via oral administration.
Dihexa
An orally active hexapeptide derivative of angiotensin IV, characterised in academic research as among the most potent known pro-cognitive compounds in animal models.
Read profileNoopept (Peptide Note)
A small proline-containing dipeptide derivative — technically a peptidomimetic — developed in Russia as an orally active cognitive enhancer with structural lineage to piracetam.
Read profileCycloprolylglycine
An endogenous cyclic dipeptide that is also the primary active metabolite of Noopept, with intrinsic anxiolytic and cognitive effects independent of its parent compound — a research peptide in its own right.
Read profileSemaglutide
A long-acting GLP-1 receptor agonist licensed for type-2 diabetes and obesity, with Phase III Alzheimer's disease trials (EVOKE and EVOKE Plus) that did not show slowed clinical progression (Lancet, 2026).
Read profileDDAVP (Desmopressin)
A licensed synthetic vasopressin analogue with documented memory-modulation effects — one of the classical vasopressin-family cognitive research peptides with the deepest historical literature.
Read profileKPV
The α-MSH 11-13 tripeptide fragment (Lys-Pro-Val) with anti-inflammatory activity mediated through melanocortin-receptor-adjacent mechanisms — studied for gut, skin, and emerging neuroinflammation research applications.
Read profileCarnosine
An endogenous dipeptide (β-alanyl-L-histidine) with distinctive antioxidant, anti-glycation, and metal-chelating properties supporting cellular-protection research applications spanning neuroprotection, cognitive-ageing, and metabolic-cognitive contexts.
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