Mechanism tag
Synaptogenic peptides
Peptides that drive new synapse formation directly through growth-factor-receptor agonism rather than indirectly through neurotrophin induction.
Dihexa
An orally active hexapeptide derivative of angiotensin IV, characterised in academic research as among the most potent known pro-cognitive compounds in animal models.
Read profileFGL Peptide
A 15-amino-acid peptide mimetic of the FGL loop of the neural cell adhesion molecule (NCAM), studied for neurogenic, synaptogenic, and memory-enhancing effects in cellular and animal research.
Read profileP21
A small peptide derived from a neurotrophic-cytokine framework, characterised in academic research for hippocampal neurogenesis induction and anti-neuroinflammatory effects in models of cognitive ageing and Alzheimer-type pathology.
Read profileDavunetide
An 8-amino-acid ADNP-derived peptide (NAPVSIPQ) evaluated in multiple neurodegenerative disease trials — the flagship clinical-trial peptide in the synaptogenic / neuroprotective family.
Read profileARA-290 (Cibinetide)
An 11-amino-acid non-erythropoietic EPO analogue, studied for tissue-protective and neuroprotective effects mediated by the innate repair receptor (IRR) — a distinctive mechanism separated from EPO's erythropoietic activity.
Read profileIGF-1 LR3
A synthetic long-acting analogue of insulin-like growth factor 1 with reduced IGF-binding-protein affinity, providing sustained systemic IGF-1 signalling with direct hippocampal-neurogenesis implications.
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